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RankMap 0.99.0

Initial submission to Bioconductor

New Features

  • Fast, robust, and scalable reference-based cell type annotation using multinomial regression on sparse ranked expression matrices.
  • Supports both single-cell and spatial transcriptomics data.
  • Compatible with Seurat, SingleCellExperiment, and SpatialExperiment objects.
  • Core function RankMap() provides a streamlined pipeline for preprocessing, model training, and prediction.
  • Customizable preprocessing: top-K gene masking, optional binning, expression weighting, and scaling.
  • Additional functions:
    • ComputeRankedMatrix() – generate ranked matrices
    • TrainRankModel() – train multinomial GLM
    • PredictRankModel() – apply trained model to query data
    • EvaluatePredictionPerformance() – assess accuracy
  • Optimized for large datasets with significantly faster runtime than SingleR, Azimuth, and RCTD.